John F Alcorn Selected Research

interleukin-22 receptor (IL-22R)

11/2019	Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia.
4/2013	IL-22 is essential for lung epithelial repair following influenza infection.

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John F Alcorn Research Topics

Disease

34	Infections 01/2021 - 12/2008
26	Human Influenza (Influenza) 01/2022 - 10/2009
23	Inflammation (Inflammations) 12/2019 - 11/2007
20	Asthma (Bronchial Asthma) 01/2020 - 11/2007
13	Pneumonia (Pneumonitis) 12/2019 - 04/2009
7	Lung Injury 01/2020 - 10/2010
6	Respiratory Hypersensitivity 02/2016 - 11/2007
5	Fibrosis (Cirrhosis) 01/2020 - 11/2007
4	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2020 - 11/2007
4	Acute Lung Injury 01/2019 - 10/2009
4	Coinfection 07/2015 - 02/2011
4	Cystic Fibrosis (Mucoviscidosis) 01/2015 - 07/2004
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2019 - 01/2010
3	Superinfection 01/2019 - 01/2018
3	Airway Remodeling 05/2014 - 11/2007
2	Emphysema 01/2020 - 01/2011
2	Bacterial Infections (Bacterial Infection) 12/2019 - 01/2017
2	Eosinophilia 02/2016 - 11/2007
2	Metaplasia 02/2016 - 05/2008
2	Bacterial Pneumonia 07/2015 - 10/2009
2	Staphylococcal Pneumonia 02/2015 - 03/2014
2	Allergic Bronchopulmonary Aspergillosis 01/2015 - 09/2010
2	Lung Diseases (Lung Disease) 04/2014 - 04/2009
2	Communicable Diseases (Infectious Diseases) 01/2014 - 12/2013
2	Weight Loss (Weight Reduction) 01/2013 - 10/2009
1	Frailty 12/2020
1	Pulmonary Emphysema 01/2020
1	Pneumococcal Infections 11/2019
1	Pneumococcal Pneumonia 11/2019
1	Urinary Tract Infections (Urinary Tract Infection) 01/2019
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2019
1	Pyelonephritis 01/2019
1	Cystitis 01/2019

Drug/Important Bio-Agent (IBA)

24	CytokinesIBA 01/2021 - 11/2007
17	Interleukin-17 (Interleukin 17)IBA 12/2019 - 09/2008
10	Interleukin-22 (IL-22)IBA 01/2020 - 09/2008
8	Proteins (Proteins, Gene)FDA Link 06/2019 - 10/2010
7	AntigensIBA 10/2016 - 05/2008
6	ChemokinesIBA 01/2020 - 01/2011
4	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2012
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 11/2007
4	NF-kappa B (NF-kB)IBA 06/2019 - 05/2008
4	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2013
4	SteroidsIBA 02/2016 - 09/2008
4	OvalbuminIBA 05/2013 - 01/2010
3	Mitogen-Activated Protein Kinase 8IBA 01/2020 - 04/2009
3	VaccinesIBA 01/2020 - 01/2014
3	InterferonsIBA 01/2020 - 01/2019
3	Interleukin-33IBA 01/2019 - 09/2015
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 09/2008
3	Interleukin-13IBA 01/2019 - 09/2015
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2019 - 01/2012
3	Interferon Type IIBA 01/2018 - 07/2015
3	InflammasomesIBA 01/2018 - 05/2013
3	Vitamin D FDA LinkGeneric 01/2018 - 01/2012
3	Antimicrobial PeptidesIBA 07/2015 - 03/2014
3	Nitrogen DioxideIBA 05/2013 - 10/2010
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 04/2009 - 11/2007
2	Protein Disulfide-IsomerasesIBA 01/2022 - 01/2019
2	Interferon LambdaIBA 01/2021 - 01/2019
2	Influenza Vaccines (Influenza Vaccine)FDA Link 12/2020 - 12/2017
2	JNK Mitogen-Activated Protein KinasesIBA 01/2020 - 05/2012
2	Bleomycin (Blenoxane)FDA LinkGeneric 01/2020 - 04/2009
2	Phosphotransferases (Kinase)IBA 01/2020 - 05/2014
2	SmokeIBA 01/2020 - 01/2011
2	interleukin-22 receptor (IL-22R)IBA 11/2019 - 04/2013
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2018
2	Lipocalin-2IBA 01/2019 - 01/2012
2	LigandsIBA 01/2019 - 10/2009
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2018 - 01/2013
2	MicroRNAs (MicroRNA)IBA 04/2017 - 05/2014
2	Immunoglobulin E (IgE)IBA 01/2017 - 10/2016
2	AllergensIBA 10/2016 - 10/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 09/2015 - 04/2014
2	Receptor for Advanced Glycation End ProductsIBA 09/2015 - 10/2012
2	Cholecalciferol (Vitamin D3)FDA Link 01/2015 - 09/2010
2	Oxidants (Oxidizing Agents)IBA 05/2013 - 10/2010
1	Neuraminidase (Sialidase)IBA 01/2022
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	LOC14IBA 01/2022
1	Angiotensin-Converting Enzyme 2IBA 12/2019
1	Carrier Proteins (Binding Protein)IBA 11/2019
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 10/2019
1	Small Interfering RNA (siRNA)IBA 06/2019
1	suvratoxumabIBA 01/2019
1	ProcalcitoninIBA 01/2019
1	Rosiglitazone (Avandia)FDA Link 01/2019
1	MEDI8852IBA 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	Viral ProteinsIBA 01/2019
1	Virulence Factors (Pathogenicity Factors)IBA 01/2019
1	Interleukin-15 (Interleukin 15)IBA 01/2019
1	AlarminsIBA 01/2019
1	CXC ChemokinesIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019
1	Interleukin-4 (Interleukin 4)IBA 01/2019
1	PPAR gammaIBA 01/2019

Therapy/Procedure

5	Therapeutics 01/2020 - 01/2010
2	Intranasal Administration 05/2014 - 05/2013